Q7: Which of the followings is P450
inducer?
a) Isoniazid
b) Phenobarbitone
c) Ketoconazole
d) Cimetidine
Correct Answer: b
Explanation:
Phenobarbitone is one of the
anticonvulsant. Anticonvulsants in general are inducers of Cytochrome P450
system. Others inducers of P450 are: Rifampin, Griseofulvin, Carbamazepine,
Phenytoin.
For inhibitors of P450 remember the
Mnemonic: SICK EGgs inhibit your appetite.
S: Sulfonamides
I: Isoniazid
C: Cimetidine
K: Ketoconazole
E: Erythromycin
G: Grapefruit juice.
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