Q9: Gastroesophageal junction
competence is increased by:
a) Lying supine
b) Paralysis of the diaphragm
c) Use of Morphine
d) Use of Metoclopromide
e) Increased intra-abdominal
pressure
Correct Answer: d
Explanation:
Metoclopromide is D2 receptor
antagonist that increased the resting tone of GIT, increases contractility
& increases Lower esophageal junction tone. It is clinically used
for Diabetic & post-surgery gastroparesis. Toxicity includes parkinsonian
effects, restlessness, drowsiness, fatigue, depression, nausea, diarrhea.
Contraindicated in patients with small bowel obstruction.
Other option under this question
actually decrease the GE junction tone.
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