1.An eight year old boy presented to the casualty with high fever, pruritic erythematous rash, joint pain and lymph node enlargement. There is a history of upper respiratory tract infection for which he was on cefaclor – 8 days completed of a 10 day course. The most likely diagnosis is? A. Serum sickness like illness B. HSP C. Type III hypersensitivity D. Kawasaki disease Correct answer : A. Serum sickness like illness Serum sickness like reaction can occur following the use of certain drugs, especially cefaclor in children. It presents with an urticarial / purpuric rash, arthritis, lymphadenopathy and fever. But unlike true serum sickness (a type III hypersensitivity response), it is not caused by circulating immune complexes. 2.A one year old child presented to the OPD with the history of short stature, tiredness and constipation. Examination revealed a palpable goitre. Serum T4 was decreased and TSH levels were ...
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