Saturday 19 April 2014

FCPS part 1 Medicine solved mcqs with explanation Q 17



Alpha-1 receptor stimulation causes:
a) Pupillary dilatation
b) Increased heart rate
c) Increased contractility
d) Increased gastric motility


Correct Answer: a


Explanation:
Apha-1 receptor causes
  • Increased smooth muscles contraction, such as in arterioles where it increases TPR & so BP
  • Increased pupillary muscle dilatation (mydriasis)
Increased heart rate (choice b) & increased contractility (choice c) of heart, although a function of sympathetic system, is not mediated by alpha-1 receptors rather it is mediated by Beta-1 receptor stimulation in heart.
Also increased gut motility (choice d) is purely a parasympathetic function.


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