Q21: Dose of Gentamicin is reduced
in the elderly due to:
a) Liver failure
b) Reduced renal function
c) Decreased GI absorption
d) Decreased metabolism
Correct Answer: b
Explanation:
Gentamicin is one of the
Aminoglycosides. In elderly like all other body functions renal function is
also slightly reduced. For Aminoglycosides such as Gentamicin, remember the
following three important side effects:
- Ototoxicity
- Nephrotoxicity
- Neurmuscular dysfunction
- Teratogenic
Aminoglycosides are used for severe
gram negative rod infections. Since they require oxygen for their uptake, they
are therefore ineffective against anaerobes.
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