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FCPS part 1 Medicine solved mcqs with explanation Q25

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Patient after an ischemic attack has ventricular Tachycardia. Drug of choice is:
a) Amiodrone
b) Metoprolol
c) Lidocaine
d) Verapamil

Correct Answer: c

Explanation:
Lidocaine is classified as a class Ib anti-arrhythmic drug. It is also used as a local anaesthetic. It selectively blocks sodium channels in depolarized cardiac cells (e.g; ischemic cardiac muscle). It is therefore considered as a first line drug in ventricular tachycardia in acute MI or after cardiac surgery. It is given through the IV route.
Adverse effects of Lidocaine:
  • high concentrations may cause bradycardia, hypotension and even asystole
  • in 10% of patients may induce ventricular arrhythmias
  • GI upset with nausea and vomiting
  • CNS: parasthesiae, twitching and generalized tonic-clonic seizures
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