FCPS part 1 Medicine solved mcqs with explanation Q25

Patient after an ischemic attack has ventricular Tachycardia. Drug of choice is:

a) Amiodrone

b) Metoprolol

c) Lidocaine

d) Verapamil

Correct Answer: c

Explanation:

Lidocaine is classified as a class Ib anti-arrhythmic drug. It is also used as a local anaesthetic. It selectively blocks sodium channels in depolarized cardiac cells (e.g; ischemic cardiac muscle). It is therefore considered as a first line drug in ventricular tachycardia in acute MI or after cardiac surgery. It is given through the IV route.

Adverse effects of Lidocaine:

• high concentrations may cause bradycardia, hypotension and even asystole
• in 10% of patients may induce ventricular arrhythmias
• GI upset with nausea and vomiting
• CNS: parasthesiae, twitching and generalized tonic-clonic seizures