1. Which medication is most likely to produce
inflammation of
the
bladder?
A. alpha-methyldopa
B. cyclophosphamide (*)
C. gentamicin
D. penicillin
E. simvastatin
2. Which is most likely to cause a
false-positive test for the
presence
of glucose in the urine?
A. hypochlorite bleach (*)
B. L-dopa
C. megadose vitamin C
D. renal glycosuria
E. zinc administration for the common cold
3. The familiar "coffin lid" crystals
in urine are composed of:
A. calcium oxalate
B. cysteine
C. magnesium ammonium phosphate (*)
D. tyrosine
E. uric acid
4. What's a reasonable "upper limit for
normal" for a count of
red
cells in the urinary sediment?
A. there should be none at all
B. 2 per high power field (*)
C. 6 per high power field
D. 50 per high power field
E. all that matters is whether you see red cell
casts
5. Acute mercury poisoning will most severely
damage which
portion
of the kidney?
A. glomerular capillary endothelium
B. glomerular podocytes
C. proximal tubule (*)
D. renal medullary structures
E. renal pelvis where urine is concentrated
6. Amyloid in the kidney is most likely to
declare itself first
by
causing
A. acute renal shutdown
B. heavy proteinuria (*)
C. red cell casts
D. renal glycosuria
E. hypertension
7. In bacterial endocarditis, you are most
likely to see what
pattern
of immune complex
deposition?
A. coarsely granular (*)
B. finely granular
C. linear
D. mesangial
E. vessel walls only
8. In Henoch-Schonlein purpura with severe
renal involvement
and
crescentic glomerulonephritis,
the
crescents themselves are most likely to stain positive for:
A. C3 but not C4 as this is alternate-pathway
B. fibrin (*)
C. IgA
D. IgE
E. IgM
9. Which is a risk factor for both renal cell
carcinoma and
transitional
carcinoma of the renal
pelvis
and bladder?
A. alcohol abuse
B. dye industry job
C. mercury diuretics
D. tobacco smoking (*)
E. von Hippel-Lindau
10. Which glomerular lesion tends to become
superimposed on most
other
kidney diseases as
renal
function begins to fail?
A. diffuse glomerulosclerosis
B. diffuse proliferative glomerulonephritis
C. focal-segmental glomerulosclerosis (*)
D. segmental necrotizing glomerulonephritis
E. wire-loop nephritis
11. Which is NOT a risk factor for acute
pyelonephritis?
A. diabetes mellitus
B. nephrolithiasis
C. prostatism
D. simple cysts (*)
E. ureterovesical reflux
12. Patients with von Gierke's glycogen storage
disease, or with
Lesch-Nyhan
syndrome, are likely
to
suffer kidney damage due to
A. accumulation of storage product
B. autoimmune interstitial nephritis
C. immune complex deposition
D. uric acid deposition (*)
E. vascular stenosis
13. What is "Bright's riddle"?
A. Why do most immune complex deposits appear
on the far side
of
the GBM, away from
where
we'd think they formed?
B. Why do patients with finely-granular kidneys
tend to have
(*)
hypertrophied hearts?
C. Why do patients with one narrow renal artery
tend to be
hypertensive
and have a finely-
granular
kidney on the opposite side?
D. Why is the excretion of urine so closely
associated
anatomically
with the sex organs?
E. Why would "bright" people try to
ride a mechanical bull when
they're
drunk?
14. Very large subendothelial immune complex
deposits suggest:
A. Goodpasture's disease
B. dense deposit disease
C. diabetes
D. lupus (*)
E. shock kidney
15. "Masugi nephritis" is the classic
animal model for
A. acute tubular necrosis
B. autoimmune interstitial nephritis
C. anti-GBM disease (*)
D. membranous glomerulopathy
E. post-streptococcal glomerulonephritis
16. Which is LEAST LIKELY to develop into
malignant
hypertension?
A. cocaine abuse
B. hemolytic-uremic syndrome
C. medullary sponge kidney (*)
D. neglected "benign" high blood
pressure
E. scleroderma
17. Finely-granular immune complex deposits
around the TUBULES
is
most suggestive of:
A. acute tubular necrosis
B. hemolytic-uremic syndrome
C. lupus (*)
D. medullary sponge kidney
E. myeloma kidney
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