Blood obtained through skin puncture (capillary blood) differs from
blood that is obtained through venipuncture. When analyzing the major
characteristics of capillary blood, such as pH, PCO2, PO2
and oxygen saturation, freely flowing capillary blood is actually more
similar to arterial than to venous blood. On the other hand, due to the
method of collection, capillary blood is contaminated with interstitial
and intracellular fluids, which will influence the analytic values
obtained from these samples. It is for this reason that capillary blood
is not recommended for coagulation testing. Differences also exist
between venous and capillary blood analyte concentrations (see table
below). This is by no means an exhaustive list, and since the data were
taken from two different studies, does not include identical analytes
for both specimen types, i.e. plasma and serum.
Differences in Composition of Capillary and Venous Blood Specimen |
informative...
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ReplyDeleteHemolysis is least likely to occur in specimens drawn via venipuncture using a closed, evacuated collection system
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