CNS MCQs Past papers MBBS

2.   What is malformed in a coloboma?

A.   cornea and conjunctiva

B.   iris and ciliary body (*)

C.   lens and its suspensory ligament

D.   retinal blood vessels

E.   retinal cell layers

3.   In sudden blindness caused by anti-recoverin antibodies, the

usual underlying cause is

A.   lung cancer (*)

B.   Lyme spirochete infection

C.   multiple sclerosis

D.   recent viral infection

E.   temporal arteritis

4.   You might ask for genetic analysis of the alpha-synuclein

gene when you are investigating for

A.   familial Alzheimer's

B.   familial parkinsonism (*)

C.   familial prion disease

D.   malignant potential of a glioma

E.   progressive supranuclear palsy

5.   What virus is the cause of tropical spastic paralysis?

A.   Epstein-Barr

B.   HIV

C.   HTLV-I (*)

D.   herpes 8 / KSHV

E.   rhabdovirus

6.   Which is the most common neuropathology lesion caused by

Lyme disease?

A.   demyelination of the posterior columns

B.   giant cell encephalitis

C.   microglial nodules

D.   polyneuropathy (*)

E.   windswept cortex with loss of neurons diffusely

7.   Binswanger's is caused by

A.   alcohol abuse

B.   arsenic exposure (suspected but not proved)

C.   hypertensive small-artery disease (*)

D.   iron overload

E.   mutant genes affecting myelin processing

8.   Which is the most common location for a hypertensive

intracerebral bleed?

A.   cerebellum

B.   cortical gray matter

C.   pons

D.   putamen (*)

E.   thalamus

9.   A pathologist's report of "anisomorphic gliosis" indicates

A.   ammonia accumulation in the bloodstream

B.   healing by gliosis

C.   manganese toxicity

D.   neoplasia (*)

E.   slow virus infection

10.  In addition to folic acid deficiency, what other nutritional

problem is believed to help cause neural

tube defects?

A.   vitamin A deficiency

B.   vitamin A toxicity (*)

C.   vitamin B12 deficiency

D.   vitamin D deficiency

E.   vitamin D toxicity

11.  Neurons at which location are considered to be the most

vulnerable to hypoxic injury?

A.   basis pontis

B.   hippocampus (*)

C.   inferior olive

D.   precentral motor cortex

E.   putamen